Realizing the need for a Congregational church in the growing community of Wyoming, Michigan, the Burlingame Congregational Church opened a new charter on April 28, 1924 and a new building was dedicated on December 4, 1925. The Rev. Arden served as the church's first pastor from 1925 to 1929. Rev. Francis Burchell served as interim pastor for two years following Rev. Arden’s departure and was succeeded by Rev. Alfred Allard who served from 1931 to 1936. Financial problems plagued the church during the Depression, along with the loss of membership. Rev. Edwin Richard Evans was assigned to help revive the church. Over the next seventeen years the church prospered. Membership grew. The building was enlarged and an organ was purchased.

By 1949 the church had 328 members with 200 in the church school. An extended basement was built to provide additional space for the church school. When Rev. Evans retired in 1954, Rev. Homer Dalrymple arrived and found the church crowded and in need of a new building. A committee was appointed to raise funds and ground was broken on March 2, 1958. After seventeen years, Rev. Dalrymple retired in 1971.

In 1957 the Congregational Christian Churches merged with the Evangelical and Reformed Churches and the United Church of Christ (UCC) was created. The Burlingame Church joined the UCC in the early 1960’s becoming the Burlingame Congregational United Church of Christ.

Beginning the in early 1970s, the church experienced dwindling attendance and an aging congregation through the service of four more pastors. This, combined with the rising cost of maintaining the church building, led to the decision in 2009 to disband.