The collection contains photographs, annual reports, minutes, news clippings, scrapbooks, and yearbooks about Butterworth Hospital and Nursing School. Items of interest in the collection are:

Photographs showing the interior and exterior of Butterworth Hospital, n.d., such as an operating room, ward, and group photos of the nursing school and staff.

The minutes of St. Mark's Home and Hospital, 1880-1899, and a St. Marks Annual Report, 1890.

Butterworth Annual reports, 1900-, yearbooks of the nursing school, "The Voyager," "White Caps," and "Servio," 1927-1970.

Various documents and memorabilia about the fund raising and construction of the new hospital building, c. 1920.

Advertising supplement from the Grand Rapids Press, 1973, which was done for the Centennial of the Hospital and gives a history of the hospital.