The Knights of Peter Claver, Inc. is the largest historically African-American Catholic lay organization in the United States. The Order is named for St. Peter Claver, the Spanish Priest who ministered enslaved people from Africa. The Order was founded in Mobile, Alabama and is presently headquartered in New Orleans.

The organization consists of six Divisions: Knights of Peter Claver, Knights of Peter Claver Ladies Auxiliary, Junior Knights, Junior Daughters, 4th Degree Knights and Ladies of Grace. The Order is governed by a Board of Directors and is under the leadership of the Supreme Knight and Supreme Lady, KPCLA. The Order is operated under the direction of the Executive Director and his staff.

The Knights of Peter Claver is divided into six Districts and States across the country. Each district or state is represented by a Deputy and other conference officers. Districts, States, and other Divisions are represented on the Board of Directors.

The Knight of Peter Claver's stated purpose is to render service to God and His Holy Church, render aid and assistance to the sick and disabled, and promote social and intellectual association among its members.